Condition	Treatment	Outcomes
Fungal infection (nail and skin)	In vitro - 10 g/L SB in SDA, incubated at 35 °C for 48 h (yeasts) or 7 days (dermatophytes and molds)	- Inhibits 80% of isolated in SDA[@348768] - Minimal inhibitory concentration 90 (MIC90) of SB: - 20 g/L for dermatophytes - 5 g/L for yeasts - 40 g/L for molds[@348768]
Fungal infection (nail and skin)	Ex vivo ^- 10 g/L of SB in SDCA, incubated at 35 °C for 48 h (yeasts) or 7 days (dermatophytes and molds)	- Fully inhibits 79% of fungal growth compared to SDCA alone[@348768]
Skin preparation for intravascular catheter placement	- 75% Isopropyl alcohol alone vs. 5% SB in distilled water, 40 - 45°C pre-treatment	- Reduced pain score in 74% patients (p < 0.001)[@348771] - 78% of nurses reported higher procedural satisfaction[@348771]
Skin preparation for intravascular catheter placement	- Talcum powder vs. 5% SB in distilled water, 40-45°C	- Shorter preparation time: 5.58 ± 1.52 vs 9.74 ± 1.23 min, p < 0.001)[@348772] - Higher patients (95%) and nurses' satisfaction (90%)[@348772]
Analgesia	- 8.4% SB at ratio 1 mL:10 mL 1% lidocaine with 1:100,000 epinephrine	- Neutralizes acidity and mitigates burning pain with infiltration[@348775]
Psoriasis	- 300 - 500 g of SB in 85 L of bathwater (approximately 0.67- 0.96 cup/tub or bath) on alternating days for 21 days	- Almost complete clearance: n = 2 (10.5%), PASI 12 to 1.6 - Significant improvement: n = 4 (21%), PASI 5.5 to 2.2 - Moderate improvement: n = 8 (42.1%), PASI 5.4 to 3.3¹³
Aquagenic pruritus	- 25 - 200 g SB in bath–titrate to effective dose. - SB paste applied topically	- Relieve and prevent pruritus[@348780]
Shampoo alternative	- Risk of hair damage with undiluted SB - SB wash could be followed by ACV rinse to help restore pH	- Decreased hair elasticity and increased breakage with undiluted SB[@348781]

Top Countries
US	622
GB	57
CA	48
IN	27
AU	26
PH	25
n/a	24
BR	22
NL	17
ID	15

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